How Long Can You Go Without Sleep? What Happens Hour by Hour
Measurable cognitive impairment begins after just 17–19 hours awake — comparable to legal alcohol intoxication. After 24 hours without sleep, judgment, memory, and coordination are significantly degraded. By 36 hours, physical health markers (inflammation, hormones, blood pressure) are measurably affected. By 48 hours, the brain begins forcing “microsleeps” — involuntary lapses of seconds at a
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