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Probiotics for Sleep: Do They Actually Work? What the Evidence Says

Probiotics show real, measurable promise for sleep — but the honest picture is more nuanced than the supplement aisle suggests. In clinical trials, certain probiotic strains have improved sleep-quality scores, and a meta-analysis of insomnia studies found probiotics produced a significant improvement in the widely-used Pittsburgh Sleep Quality Index. The likely main mechanism is indirect:

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SIBO and Sleep: Why Bacterial Overgrowth Wrecks Your Rest

SIBO — small intestinal bacterial overgrowth — happens when bacteria that normally live in the large intestine proliferate in the small intestine instead, where they ferment food and produce excess gas. The result is bloating, abdominal discomfort, cramping, and sometimes diarrhoea or constipation, and these symptoms are directly sleep-disrupting: it’s hard to fall asleep, or

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