September 2026

Peptides and Sleep: What the FDA Panel Actually Voted On

In July 2026, the FDA’s Pharmacy Compounding Advisory Committee narrowly recommended six experimental peptides, including Epitalon, which is promoted for sleep and longevity, for the 503A Bulks List, a decision that has already generated significant scrutiny. Three things are worth understanding clearly. First, this vote is not FDA approval: it’s a recommendation about whether compounding

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CGM and Sleep: What the New Research Actually Shows

Continuous glucose monitors (CGMs) have moved from a diabetes management tool into a mainstream biohacking product, now available over the counter without a prescription (Dexcom’s Stelo, Abbott’s Lingo), often marketed with promises about optimizing sleep through glucose insights. The underlying bidirectional relationship between sleep and blood glucose is real and reasonably well-established, but mostly in

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Reishi Mushroom for Sleep: The New Trial, With a Caveat

Reishi mushroom (Ganoderma lucidum) has over 2,000 years of traditional use in East Asian medicine as a calming tonic, and it contains compounds, triterpenes (ganoderic acids) and beta-glucan polysaccharides, with plausible mechanisms for supporting sleep, including GABA receptor activity and modulation of the stress-response (HPA axis) system. Most of this mechanistic evidence, though, comes from

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